Methylome analysis yielded no significant match to a reference methylation class in the DKFZ brain tumor methylation classifier (v11b4).4 The copy-number profile showed a CDKN2A/B deletion, but no amplification of chromosome 7, loss of chromosome 10, or EGFR amplification (Figure 3B). The gene discussed is CDKN2A; the disease is brain neoplasm.