IL6 and hydrops fetalis: Inflammatory factors, including interleukin-1 β (IL-1β), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), CRP, and interleukin-17A (IL-17) have been found to be inversely associated with cognitive functions in HF patients (59) as these remain significant after changes in LVEF and symptoms of HF.