Redwine LS et al. investigated outpatients with HF and found that lower MoCA scores are associated with higher levels of plasma inflammatory biomarkers, such as interferon-γ (IFN-γ), tumor necrosis factor-α (TNF-α), and soluble vascular cell adhesion molecule-1 (sVCAM-1) (129). This evidence concerns the gene VCAM1 and hydrops fetalis.