NTSR1 and schizophrenia: In the CNS, NT exerts various effects, including analgesia (Clineschmidt and McGuffin, 1977) and central control of blood pressure (Rioux et al., 1981), is involved in the pathophysiology of schizophrenia and Parkinson’s disease, with levels of endogenous NT and NTSR1 expression decreased in patients with the symptoms of schizophrenia (Nemeroff, 1980) (Clineschmidt and McGuffin 1977; Yamada et al., 1995; St-Gelais et al., 2006).