When use of insulin or ACE inhibitors/ARBs was added to the multivariate logistic regression model, use of XOR inhibitors remained significantly associated with sarcopenia (OR 0.467, 95% CI 0.228–0.957, p = 0.038; OR 0.463, 95% CI 0.226–0.948, p = 0.035, respectively) and severe sarcopenia (OR 0.238, 95% CI 0.091–0.620, p = 0.003; OR, 0.236, 95% CI 0.091–0.614, p = 0.003, respectively). This evidence concerns the gene INS and sarcopenia.