, cytokines (IL-1, IL-6, IL-8), chemokines (CXC chemokines CXCL1 to CXCL12, CC chemokines CCL2 and CCL20), enzymes (LOX family oxidases and LOX-like proteins 1–4, COX2), matrix metalloproteinases (MMP-1, MMP-2, MMP-7, MMP-9, MMP-13, and MMP-14), ECM proteins (fibronectin, collagen I and III, EDA-fibronectin, tenascin C, and SPARC), and metabolic intermediates that are secreted during the exchanges (between various molecular information) associated with stromal and cancer cells transitions. This evidence concerns the gene FN1 and cancer.