MUC16 and Pleural effusion: However, after adjustments in the final multivariate models (Table 3), having no comorbidity and serum CA-125 levels of ≤370 U/mL (OR = 6.80; 95% CI = 1.19, 38.79; P = 0.031) and the absence of any radiological evidence of pleural effusions (OR = 5.60; 95% CI = 1.32, 23.71; P = 0.019) and enlarged retroperitoneal lymph nodes were the only independent predictors of optimal PDS.