For example, luteolin enhanced autophagy and antioxidative processes in both in vivo and in vitro models of intracerebral hemorrhage [32], protected heart tissues in STZ-induced diabetic mice through modulating Nrf2-mediated oxidative stress and NF-κB-mediated inflammatory responses, and alleviates aflatoxin B1-induced apoptosis and oxidative stress in the liver of mice through activation of the Nrf2 pathway [33]. This evidence concerns the gene NFKB1 and intracerebral hemorrhage.