For CCl4-induced fibrosis, mice were administered CCl4 twice a week for 6 weeks and then infused with Exo-Decoy RBP-J or Exo-Decoy Control ODNs (200 μg/mouse) via the tail vein 24 h after the 9th to 12th injection of CCl4 (Figure 5A). The gene discussed is RBPJ; the disease is fibrosis.