Both MON1A (Rho = -0.19, adj.p = 0.01) and RAB7 (Rho = -0.22, adj.p = 0.003) mRNA expression demonstrated a negative correlation with CDR score only in the parahippocampal gyrus (BM36) which is particularly vulnerable to AD (Figure 2A-B), but not in other brain regions, indicating a region-specific impact of AD on these genes. The gene discussed is MON1A; the disease is Alzheimer disease.