Through the tests by western blot of STAT1 and STAT3, it revealed that the phosphorylation levels of STAT1 and STAT3 in the spleens of aged sepsis model rats were greatly increased at all time points compared with those in the spleens of normal rats, and maximal phosphorylation was observed at 24 h (Figures 5C–F). The gene discussed is STAT1; the disease is Sepsis.