TNFRSF9 and colon carcinoma: Importantly, the total number of Tregs was decreased in both models (Figures 6D, G, left) and was significantly decreased in the colon carcinoma model after Wt-mAb treatment (P=0.007, Figure 6D, left); however, the CD137+ Treg/Treg ratio was unchanged (Figures 6D, G, right).