C57BL/6 mice were i.p. administered with Ebastine (5 mg/kg) or Loratadine (10 mg/kg) 1 day before viral inoculation and the treatments were continued daily throughout infection (Figure 5A), and the blocked degranulation from splenic c-Kit+ FcεRI+ MCs were observed, as indicated by the rescued immunostaining of cytoplasmic avidin granules (Figure 5B). This evidence concerns the gene KIT and infection.