To discover small molecules that target IL-6/Laminin α5/FAK signaling in lung cancer, we first performed compound screens in two cell lines (IL-6-GFP PC-9 cells and IL-6-GFP PC-9GR cells) using a small molecule library comprising 510 compounds (Fig. 5a and Supplementary Data 3). This evidence concerns the gene PTK2 and lung carcinoma.