AGT and COVID-19: It is suggested that thrombotic microangiopathy instead of DIC is manifestation of coagulopathy in COVID-19 patients with kidney injury.237–239 Glomerular ischemia and endothelial cell damage also appear in some cases.240 Glomerular ischemia was observed in patients with fibrin thrombi in the glomerular capillary loops, which may be related to coagulation activation in COVID-19 patients.6,241 In addition, an interaction between Ang II overactivity, and complement pathways could also influence AKI severity and outcomes.