IFNG and neoplasm: Consistent with this, vaccination by blood-derived DCs, stimulated with protamine/mRNA and loaded with three tumour-associated antigens (NY-ESO-1, MAGE-C2 and MUC) resulted in more frequent detection of tetramer/dextramer-positive (dm+) and interferon-gamma (IFN-γ)-producing antigen-specific T cells in skin biopsy samples of patients with radiologic non-progressive disease versus patients with CRPC with progressive disease; the overall median radiologic progression-free survival was 9.5 months [40].