To elucidate the molecular mechanisms how combination treatment suppresses the proliferation and survival of docetaxel-resistant PCa cells, we performed high-throughput Micro-Western Array (MWA) (Fig. 6A) to evaluate the expression level of 96 proteins involved in cell cycle regulation, apoptosis, AKT signaling, cholesterol efflux and metabolism. Here, AKT1 is linked to posterior cortical atrophy.