In the network, hsa-miR-15a-5p potentially target and silence RACGAP1, SPC24, KIF18B, CDCA7L, and ANLN; hsa-miR-30a-5p potentially target and silence CENPM; hsa-miR-148a-3p potentially target and silence VIPR1, PRR11, ANLN, and PRC1; hsa-miR-199a-5p potentially target and silence CDCA7L, CENPM, E2F2, RNF152, KIF2C, CHEK1, CDC6 and MCM10. Silencing these genes could repress HCC progression through multiple mechanisms. This evidence concerns the gene CENPM and hepatocellular carcinoma.