Moreover, CAT in female patients was positively correlated with hypertension (OR 1.54, 95% CI 1.07–2.22, P = 0.021) and HDL (OR 1.86, 95% CI 1.07–3.24, P = 0.028), and negatively correlated with obesity (OR 0.51, 95% CI 0.31–0.84, P = 0.008), while it in male patients was positively associated with age (OR 1.03, 95% CI 1.02–1.04, P < 0.0001) and negatively associated with overweight (OR 0.72, 95% CI 0.56–0.94, P = 0.014) and obesity (OR 0.46, 95% CI 0.32–0.66, P < 0.0001) (Tables 5 and 6). This evidence concerns the gene CAT and obesity due to melanocortin 4 receptor deficiency.