Contrary to the above-mentioned study performed in the absence of infection and suggesting that B cell development and antibody production are not affected by CD84 deficiency (35), morphometric analysis here indicated that, while the average size of GCs was the same in M. tuberculosis-infected CD84-deficient and WT mice at 60 days postinfection, the area occupied by GC clusters was greater in M. tuberculosis-infected CD84-deficient mice than in M. tuberculosis-infected WT mice (Fig. 4g and h). Here, CD84 is linked to infection.