UBE2D2 and non-small cell lung carcinoma: In addition, it was also found that up-regulation of miR-376a-3p could reverse the positive regulation of up-regulated circ-UBE2D2 on EIF4G2 expression, and also turned around the promoting effect of elevated circ-UBE2D2 on NSCLC progression (Attached Figure 1(a-f)), which further proved the conclusion.