Up-regulated Kyoto Encyclopedia of Genes and Genomes (KEGG) terms included protein digestion and absorption, cyclic adenosine 3′,5′-monophosphate signaling pathway, insulin secretion, maturity onset diabetes of the young, type II diabetes mellitus, and growth hormone synthesis, secretion, and action (Fig. 3G). The gene discussed is GH1; the disease is type 2 diabetes mellitus.