doi:10.7326/0003-4819-115-4-256 Bovill EG, Terrin ML, Stump DC, Berke A.D, Frederick M, Collen D, et al. (1991) Hemorrhagic events during therapy with recombinant tissue-type plasminogen activator, heparin, and aspirin for acute myocardial infarction: results of the thrombolysis in myocardial infarction (TIMI), Phase II Trial. Here, PLAT is linked to acute myocardial infarction.