doi: 10.1186/s13098-015-0029-0 Deng W, Li C, Zhang Y, Zhao J, Yang M, Tian M, et al. Serum C1q/TNF-related protein-3 (CTRP3) levels are decreased in obesity and hypertension and are negatively correlated with parameters of insulin resistance. Here, C1QTNF3 is linked to obesity due to melanocortin 4 receptor deficiency.