These differences suggest that KGF may play a role in the mechanism of PC formation and that its effect is more significant in the initial stages of cyst development, possibly similar to its epithelial proliferative effect during wound healing.11,30 KGF expression was not significantly different to the intensity and type of inflammatory infiltrates, contrasting with the information reported in the literature.6 Epithelial cells were the cell types with greater KGF expression, but comparing atrophic and hyperplastic epithelia showed no statistical difference. Here, FGF7 is linked to pachyonychia congenita.