Most of the top 10 highly expressed genes (TP73L, CSTA, KRT5, DSG3, TRIM29, FOSL1, NEDD1, CALML3, CSRP2, and PMAIP1) sorted by FDR were also highly expressed in colorectal adenocarcinoma tissues, such as TP73L (also known as TP63)17, 18 and TRIM29.19 Here, KRT5 is linked to colorectal adenocarcinoma.