Furthermore, ethanolamine kinase 1 (ETNK1) is a rate‐controlling enzyme in phosphatidylethanolamine biosynthesis, and its low expression would promote the proliferation and invasion of gastric cancer, larynx‐ or tongue‐derived squamous cell carcinoma, among others,68, 69, 70 indicating that TBPL1 would promote glioma tumorigenesis via the NPAS2/CRY2/NR4A2/ETNK1 pathway. This evidence concerns the gene ETNK1 and central nervous system cancer.