Furthermore, ethanolamine kinase 1 (ETNK1) is a rate‐controlling enzyme in phosphatidylethanolamine biosynthesis, and its low expression would promote the proliferation and invasion of gastric cancer, larynx‐ or tongue‐derived squamous cell carcinoma, among others,68, 69, 70 indicating that TBPL1 would promote glioma tumorigenesis via the NPAS2/CRY2/NR4A2/ETNK1 pathway. The gene discussed is CRY2; the disease is central nervous system cancer.