Fourteen genes within the tumour immune microenvironment pathway (AC020907.1, Y_RNA, TMEM72‐AS1, KRT16P2, DLX6‐AS1, AP002414.1, hsa‐miR‐424, TBPL1, NPAS2, CRY2, VPS33B, CT62, DPY19L2P1, and KCNH1‐IT1) were used to construct a model to evaluate the importance of these genes in malignant glioma. The gene discussed is CRY2; the disease is malignant glioma.