ILK and neoplasm: Especially, signaling events downstream of β1 integrins involving focal adhesion kinase (FAK), integrin-linked kinase (ILK), and the phosphatidylinolsitol-3-kinase (PI3K)/Akt axis mediate radio- and chemoresistance in many tumor entities (Hehlgans et al. 2007; Eke et al. 2010; Graham et al. 2011).