In this case-control study of oil workers in Karamay, Xinjiang, adjusting for confounding factors, mutant genes at the A1298C polymorphism and the C677T polymorphism of the MTHFR gene were found to be susceptible genotypes for hypertension, which is consistent with the findings of and Alghasham et al. (2012). Here, MTHFR is linked to hypertensive disorder.