Delivery of ONO1301, a stable small molecule PGI2 agonist on an epicardial collagen patch in a model of dilated cardiomyopathy, demonstrated expression of Hepatocyte Growth Factor (HGF), Vascular endothelial growth factor (VEGF), Stromal cell-derived factor-1 (SDF-1), and G-CSF. Here, CXCL12 is linked to dilated cardiomyopathy.