This was shown by dramatically reduced tumor cell proliferation (Ki67) (Fig. 2C, first panels, and Fig. 2D), angiogenesis (endomucin) (Fig. 2C, second panels, and Fig. 2D), ROS-induced DNA damage (8-OxodG) (Fig. 2C, third panels, and Fig. 2D), and hypoxia (CA-IX) (Fig. 2C, fourth panels, and Fig. 2D). Here, EMCN is linked to neoplasm.