We further validated these data in human BC cells, showing that the fraction of cells expressing p-AMPK and GLUT1 was increased upon GPx2 KD in MDA-MB-361 cells (SI Appendix, Fig. S11 A–D), and decreased upon GPx2 OE in MDA-MB-231 cells (SI Appendix, Fig. S11 E–H). This evidence concerns the gene GPX2 and breast cancer.