EMCN and neoplasm: Interestingly, compared to the regularly shaped PyMT tumor vessels, which displayed colocalized lectin-TRITC with endomucin-FITC in most vessels (SIAppendix, Fig. S5A), GPx2 KD tumor vessels were devoid of lectin-TRITC at the endothelial cell membrane (SI Appendix, Fig. S5A).