YTHDF1 and gastric cancer: We surveyed the expression of m6A-related genes in GC tumors compared with adjacent normal tissues in TCGA cohort (online supplemental figure S1), which revealed that YTHDF1 is the most significantly altered m6A-related gene in GC and upregulation of YTHDF1 was confirmed both in paired GC cases (n=27, p<001), and overall GC cohort (GC, n=375; adjacent normal, n=32, p<0.001) (figure 1B).