Given that the loss of YTHDF1 eliminated gastric tumors in immunocompetent hosts, we next wondered if it can trigger a durable, systemic antitumor immune response that prevents future tumor implantation.24 25 In a nutshell, we divided the mice into two groups and injected the YTN16 cells with or without YTHDF1 into the right dorsal flanks of mice, respectively. The gene discussed is YTHDF1; the disease is neoplasm.