Using the identified clinical cutoff values to protect from CFH-associated AKI with near certainty indicated that patients with moderate CFH concentrations and haptoglobin concentrations greater than 2.7 g/l had a similar risk for AKI as patients with low CFH concentrations (OR moderate vs. low, 1.17 [95% CI, 0.24–5.44], P = 0.83) (Fig. 5). This evidence concerns the gene HP and acute kidney injury.