IRAK1 and esophageal squamous cell carcinoma: Moreover, Western blot analysis showed increased IRAK1 expression in radioresistant ESCC tissues of both radiosensitive (n = 46) and radioresistant (n = 36) patients (Fig. 4C), and also in radioresistant KYSE30 cells (Fig. 4D, Additional file 2: Figure S1C).