The highest concentration of serum anti-LPS-IgA was detected in patients with NPDR that had macular oedema, aneurysms, haemorrhages, and portions of solid exudate; in addition to vascular changes, much lower concentrations of anti-LPS-IgA were identified in PDR, and the lowest concentrations of antiendotoxin antibodies were found in patients with PDR complicated by neovascular glaucoma [22]. This evidence concerns the gene CD79A and macular retinal edema.