SIX1 and neoplasm: Remarkably, TUG1 expression in patients was associated with tumor size (P = 0.032), lung metastasis (P = 0.004), HBV infection (P = 0.024), AJCC stage (P = 0.008), miR-524-5p (P = 0.001), and SIX1 mRNA (P = 0.011) (Additional file 1: Table S1), whereas the expression of TUG1 was not associated with patient age or gender.