Various drugs such as vitamin E [7, 8], peroxisome proliferator-activated receptor gamma agonists [9, 10], ursodeoxycholic acid [11, 12], antioxidants [11], insulin-sensitizing agents, glucose-lowering drugs [13–18], and lipid-lowering drugs [19–21] have been used for the treatment of NASH. This evidence concerns the gene INS and metabolic dysfunction-associated steatohepatitis.