First, we analyzed RNA-Seq data of tumor-infiltrating Tc1 and Tc9 cells from s.c. B16 tumors and observed that Tc9 cells had lower expression of genes associated with lipid peroxidation and ferroptosis activation, such as Atp5g3 and Cars, whereas the expression of genes associated with ferroptosis inhibition did not change significantly as compared to Tc1 cells (Figure 2A). The gene discussed is CARS1; the disease is neoplasm.