Additionally, GNB1 was knocked down in cells with declined miR-545-3p, which manifested that GNB1 turned around repression of the miR-545-3p’s action on CRC cells (Figure 5a-f), elucidating that GNB1 mediated the impact of miR-545-3p on SW480 cells. This evidence concerns the gene GNB1 and colorectal carcinoma.