The target genes were mainly located in the cytoplasm, membrane raft, plasma membrane, etc. The molecular functions performed involve protein tyrosine kinase activity, protein phosphatase binding, epidermal growth factor receptor binding, guanylate exchange factor activity, etc. The enriched signal pathways included ErbB signal pathway, cancer pathway, proteoglycan in cancer, and neurotrophic factor signal pathway. The gene discussed is EGFR; the disease is cancer.