Sepsis significantly (p < 0.05) attenuated the mRNA expression of MLCK (Fig. 5B) in mouse aorta (0.36 ± 0.14 vs. 1.34 ± 0.37, n = 7) while MYPT1 expression (Fig. 5C) was significantly (p < 0.05) increased (3.11 ± 1.01 vs. 0.84 ± 0.24, n = 4) as compared to that observed in SO group. The gene discussed is MYLK; the disease is Sepsis.