As illustrated in Fig. 2A, sepsis did not produce significant change in Notch1 mRNA transcript expression in mouse aorta, albeit, there was 32.71% decrease in the mRNA expression as compared to SO mice (0.72 ± 0.10 vs. 1.07 ± 0.16, n = 7–8). The gene discussed is NOTCH1; the disease is Sepsis.