There is also compelling evidence to suggest that EMT facilitates colon cancer metastasis, with studies showing that EMT can be stimulated through signaling pathways such as Wnt/β-Catenin [6, 7], AKT/GSK 3β/Snail [8, 9], and PI3K/AKT [10–12]. The gene discussed is AKT1; the disease is malignant colon neoplasm.