When we next examined the correlations between percent ADM area and PanIN area, fasting insulin, fasting glucose, and body weight in individual mice at 57 weeks of age, for each genotype (orange or blue) or both together (black) (Fig. 3E–L), we found, as expected, that ADM area strongly correlated with PanIN area in non-tumor–bearing females of both genotypes (Fig. 3F). Here, INS is linked to neoplasm.