TGFB1 and renal fibrosis: Transforming growth factor β1 (TGF-β1), which is a potent fibrogenic factor and plays a crucial role in the development of renal fibrosis [7, 8], could promote the cisplatin-induced EMT of NRK-52E [9] and exert its biological functions via the p38 mitogen-activated protein kinase (MAPK) pathway in hepatitis B virus-induced tubular EMT [10].