VEGFA and intrahepatic cholangiocarcinoma: By applying the fixed-effects model (I2 = 0%, P = 0.95), the result indicated that high expression level of VEGF correlated with poor OS in patients with intrahepatic cholangiocarcinoma (pooled HR = 1.93, 95% CI 1.52–2.46; P < 0.001) (Fig. 2).