Likewise, POLD1 expression was significantly positively correlated with MSI in ACC, BLCA, BRCA, CESC, head and neck squamous cell carcinoma (HNSC), KICH, KIRC, HCC, LUAD, LUSC, PRAD, SARC, STAD, THCA, and UCEC (Supplementary Figure S3D). The gene discussed is POLD1; the disease is adrenal cortex carcinoma.