There were no statistically significant differences in the clinical manifestations between IM patients with elevated (IM2 group) and normal ALT (IM1 group), but the incidence of cervical lymphadenopathy, hepatomegaly, splenomegaly, and puffy eyelids in the IM1 and IM2 groups were significantly higher than that in the non-IM group (Table 2). This evidence concerns the gene GPT and Splenomegaly.