The expression of AGP induced by OMR1 protein in McF-7 breast cancer cells and the secretion of IL-1 β, IL-8 and TNF-α in McF-7 breast cancer cells were significantly higher than that in normal appearing tissues.There was no significant correlation between AGP expression in breast cancer tissues and e-age menopausal bed bath period, tumor length and pathological differentiation of lymph node metastasis. The gene discussed is TNF; the disease is breast carcinoma.