In this context, we recently published a prospective study in a cardiovascular cohort of 950 subjects with or without coronary artery disease (CAD) showing that high apolipoprotein CIII (Apo CIII) plasma concentration may be associated with an increased risk of ischemic stroke or transient ischemic attack (TIA) (9). The gene discussed is APOC3; the disease is transient ischemic attack.