In this series, a gold(III) complex [Au(phen)Cl2]Cl (Auphen, phen = 1,10-phenanthroline, Figure 5) (Martins et al., 2012) was found to decrease cell proliferation in AQP3-expressing cells, revealing its potential for the treatment of carcinomas with large AQP3 expression (Serna et al., 2014). The gene discussed is AQP3; the disease is carcinoma.