ALS/FTD-associated RNA-binding proteins including TDP-43, FUS, hnRNPA1, hnRNPA2, and TIA1 have been identified in multiple biomolecular condensates, and the phase separation of these RNA-binding proteins are important for the formation and function of these biomolecular condensates. The gene discussed is HNRNPA1; the disease is amyotrophic lateral sclerosis.